This province contains not only the city of Sancti Spiritus, which has been designed World Heritage Site by UNESCO, but also the city of Trinidad, considered a Museum City. This titles speak for themselves about the conservation of the architectonic treasures dating back to colonial times, with mixed styles of the 18th, 19th, and 20th centuries. When walking along Trinidad's stone-paved streets, the visitor is able to admire exquisitely manufactured attributes like ironworks, staircases, and balconies.
In the main plaza, are contrasting the profane statue of Terpsichore, Greek muse of choral songs and dance, and the Holy Trinity Church, expression of catholic religiosity. The altar and the images of this church are extremely valuable pieces.
To get to know local history, the Guamuhaya museum offers a panorama of Cuban history from its origins. The museum facility is thought to have been Hernán Cortes' residence while preparing his trip to Mexico.Other museums, like the Museo Romántico, located in the Brunet palace, and the Museo Municipal de Historia, offer details of economical and social life of the region.
Sancti Spíritus' culture is complemented by the Parque Nacional Caguanes, where there is a great deal of valuable archeological sites and pictographic murals of great interest. In addition, the section of UNEAC (association of Cuban writers and artists) in the province annually organizes a colloquy on narrative that has a national transcendence and gathers relevant figures of Cuban intellectuality.